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Leading Experts

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DAVID H. SACHS, M.D.

Professor of Surgery, Columbia University Medical Center
Professor of Surgery Emeritus, Harvard Medical School
Chief Scientific Advisor for XenoTherapeutics



David H. Sachs, M.D. specializes in transplantation medicine and immune tolerance and is an expert in xenotransplantation. Dr. Sachs’ many research achievements include the discovery of Ia (Class II) antigens and the development of monoclonal antibodies to MHC antigens. He served at the National Institutes of Health in Bethesda, where he later became the Chief of the Immunology Branch, National Cancer Institute. Dr. Sachs is a Director of the Transplantation Biology Research Center, Surgical services at Massachusetts General Hospital, and is the first Paul S. Russell and Warner-Lambert Professor of Surgery and Immunology at the Harvard Medical School. Dr. Sachs was elected to the Institute of Medicine of the National Academy of Sciences in 1996. During a sabbatical year, he was a Visiting Professor, Department of Cell Research, Wallenberg Laboratory at the University Of Uppsala, where he initiated studies of the molecular biology of transplantation antigens. Dr. Sachs subsequently returned to Massachusetts General Hospital and Harvard Medical School in his current positions. He has published over 650 articles in scientific journals. Dr. Sachs is a Member of the Editorial Board of several journals in his field. He has received many honors and awards including the Award for Distinguished Contributions to Health Research by The Medical Foundation in 2001, the Mary Jane Kugel Award by the Juvenile Diabetes Research Foundation, the Jean Borel Award in Transplantation, and the ASTP/Novartis Established Investigator Award in 1998, the AST Distinguished Achievement Award (2005), the Martin Prize for Excellence in Clinical Research in 2009, and the Thomas E. Starzl Prize in Surgery and Immunology in 2012. Dr. Sachs trained as a Surgical Intern and Research Fellow in Transplantation at the Massachusetts General Hospital. He received an M.D., magna cum laude, from Harvard Medical School, graduated from Harvard College, summa cum laude, with an A.B. in Chemistry, and received a Diplome d'Etudes Superieures de Sciences in Organic Chemistry from the University of Paris the following year where he studied as a Fulbright fellow.


JAY A. FISHMAN, M.D.

Professor of Medicine, Harvard Medical School Director,
Transplant Infectious Disease & Compromised Host Program
MGH Associate Director, MGH Transplantation Center
Infectious Disease Advisor for XenoTherapeutics


Jay A. Fishman is Director of the Transplant Infectious Diseases and Compromised Host Program at the Mass General, Associate Director of the Mass General Transplant Center and Professor of Medicine at Harvard Medical School in Boston, MA. Dr. Fishman is an internationally recognized expert in infectious diseases related to transplantation and has trained many of the leaders in this field. He has a special interest in molecular diagnostics, transplant virology and mycology, and in medical education. He is Past-President of the American Society of Transplantation and has served on the Boards of the International Transplant Infectious Disease and International Xenotransplanation Societies and of the Immunocompromised Host Society and is a frequent contributor at national and international symposia. He has been recognized by the Clinical Career Achievement Award of the American Society of Transplantation and the Transplantation Society Award for Transplant Infectious Disease. Dr. Fishman's clinical and research interests focus on the pathogenesis and prevention of infection in the immunocompromised host. His NIH-funded laboratory is investigating infectious disease issues related to xenotransplantation and the role of viral infections in transplantation. Author of the World Health Organization’s guidelines for Xenotransplantation.